Several risk factors might increase your chances of getting Peyronie’s disease:
Age. Peyronie’s disease is more likely to happen as you get older. It occurs in about 10-15% of middle-aged men.
Genetics. If you have a close relative (brother or father, for example) with the disease, you’re at a higher risk.
Connective tissue disorders. Those with a connective tissue disorder are at a greater risk. Examples of those disorders include Dupuytren’s disease, plantar fasciitis and scleroderma.
Erectile dysfunction. Men who have diabetes-associated erectile dysfunction (ED) (impotence/difficulty getting and keeping an erection) are four to five times more likely to develop Peyronie’s disease. Sometimes erectile dysfunction can be caused by having Peyronie’s.
Prostate cancer. Men who have had surgery for prostate cancer are at an increased risk.
Autoimmune disorders. If you have an autoimmune disorder like lupus, you’re more likely to get Peyronie’s disease.